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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Descript door Cialis drug generic

C.

Cialis (tadalafil) can interact with certain foods and beverages, such as grapefruit and grapefruit juice, and may enhance the blood pressure-lowering effects of the medication.

You should always speak to a doctor or pharmacist if you are using Cialis or taking any other medications for blood pressure or heart health. Cialis is doorway use with tadalafil, and while some people take it with nitrates or alpha-blockers, others may require a lower dose to experience results.

Cialis is a PDE5 inhibitor. While not a direct interaction, combining it with PDE5 inhibitors can worsen side effects and increase blood pressure-lowering benefits. Seek medical advice if any PDE5 inhibitors cause blurred vision, dizziness, lightheadedness, or fainting in your body.

D.

A Word about Generic Cialis

Generic Cialis is a popular and widely used drug for treating erectile dysfunction. It offers a convenient alternative to its brand-name counterparts, like Viagra and Levitra, which are sold under the brand name Cialis. Generic Cialis is available in a variety of dosages, including the brand name Viagra, to choose from. While the drug is generally well-tolerated, some people may experience side effects, such as headaches and back pain. It is important to note that generic Cialis should not be taken more than once per day.

How Does Generic Cialis Work?

Generic Cialis is a medication that comes in two forms:

The active ingredient in Cialis is tadalafil, which is a PDE5 inhibitor. This means that it increases the amount of blood flow to the penis, which can help men to achieve and maintain an erection. By inhibiting PDE5, Cialis can help men achieve and maintain an erection. It is important to note that Generic Cialis is not a cure for erectile dysfunction, which means that it can only be effective when prescribed by a healthcare provider.

Generic Cialis works by relaxing the smooth muscle in the walls of the blood vessels in the penis. This allows blood to flow more freely into the penis, which can cause an erection. This helps men to achieve and maintain an erection. It is important to note that Generic Cialis should not be taken more than once per day, as it may cause side effects or resistance in some people. It is also worth noting that Cialis is available in a range of dosages, including 5mg and 10mg tablets. While it is possible to buy generic Cialis in bulk to get the same results, it is not recommended for daily use.

Side Effects of Generic Cialis

Like any medication, Generic Cialis can cause side effects. The most common side effects include headache, facial flushing, and indigestion. These side effects may be temporary or may resolve on their own. In rare cases, more serious side effects like severe allergic reactions, prolonged erection (priapism), and cardiac issues have been reported. If you experience any of these side effects, seek medical help immediately.

Cost of Generic Cialis

Generic Cialis comes in several different dosages, including 5mg, 10mg, and 20mg. It is important to consider the cost of each dosage. The generic Cialis can be more affordable than the brand-name version, Cialis. Additionally, generic Cialis can be less expensive than its brand-name counterpart, Viagra. However, it is important to consider the cost of the medication when deciding on the best course of treatment. If you are experiencing any of the following side effects, seek medical help immediately:

  • Back pain
  • Flushing
  • Headache
  • Facial flushing
  • Swelling in the face, throat, or tongue
  • Indigestion
  • Swelling in the hands or feet
  • Muscle pain
  • Rash
  • Shortness of breath
  • Painful urination
  • Swelling in the eyes
  • Severe dizziness

Generic Cialis can also be more affordable than its brand-name counterpart, Cialis.

WYOMKS, Canada — Eli Lilly and Company (NYSE: LLY) today announced financial results for the third quarter of 2008.

Lilly closed its fourth-quarter full-year financial results with a $1.4 billion charge for the full-year 2008 adjusted earnings per share (EPS) of $2.42. Sales of Eli Lilly’s product Cialis (tadalafil) increased by $0.8 million to $5.07 million for the full-year 2008. Sales of Cialis were $5.05 million for the full-year 2008 compared with $4.04 million for the full-year 2008 sales. Cialis sales were $1.1 million for the full-year 2008 compared with $0.6 million for the full-year 2007 sales. Cialis’ fourth quarter 2008 adjusted EPS of $2.00 increased to $2.33.

Lilly adjusted its adjusted earnings per share (EPS) from $2.42 in 2008 to $2.33 in 2008 from $2.42 in 2007. The Company also adjusted its EPS results from $1.4 million to $1.3 million. As of December 31, 2008, Lilly was trading $5.06 million, or 2.5%, on the closing price of $0.99 in the United States.

“This is a great first-half financial performance for the Company,” said Chief Financial Officer Kevin Geller. “I am pleased to report that the company has successfully completed our third-quarter 2008 adjusted EPS of $2.40 and continues to deliver on our expectations. Our third-quarter 2008 EPS of $2.50 and the fourth quarter 2008 EPS of $2.35 are outstanding, with full year 2008 earnings per share (EPS) of $3.29. We are confident that we can continue to deliver on our 2008 EPS.”

Lilly previously reported revenue of $3.07 million, or 0.8%, for the quarter. Revenue for the quarter was $3.07 million, or 0.4%, for the third quarter of 2008. Lilly adjusted its EPS of $3.27 for 2007 from $3.27 in 2007.

Lilly’s operating results in the fourth quarter of 2008 represented a full year improvement of $1.3 million, or 0.7%, from $1.3 million in the fourth quarter of 2008. Sales of Lilly’s brand Cialis (tadalafil) rose by $0.7 million in the quarter to $3.07 million. Sales of Cialis were $3.07 million for the quarter. Sales of Lilly’s Cialis brand Viagra (sildenafil) were $3.07 million for the quarter.

For the quarter, the Company reported full-year 2008 EPS of $2.39, or 0.7%, for the third quarter of 2008. Reported net income was $1.06 million, or 0.4%, for the third quarter of 2008. For the quarter, the Company reported full-year 2008 EPS of $2.36, or 0.6%, for the third quarter of 2008. Net income was $1.06 million, or 0.5%, for the quarter. For the quarter, the Company reported full-year 2008 EPS of $1.15, or 0.5%, for the third quarter of 2008.

For the quarter, reported net income was $1.08 million, or 0.3%, for the third quarter of 2008. The Company reported full-year 2008 EPS of $1.08, or 0.5%, for the third quarter of 2008. Net income was $1.08 million, or 0.4%, for the quarter. For the quarter, the Company reported full-year 2008 EPS of $1.04, or 0.6%, for the third quarter of 2008.

For the quarter, reported net income was $0.08 million, or 0.2%, for the third quarter of 2008. The Company reported full-year 2008 EPS of $0.14, or 0.7%, for the quarter. Reported net income was $0.09 million, or 0.4%, for the quarter. For the quarter, the Company reported full-year 2008 EPS of $0.09, or 0.7%, for the quarter. Reported net income was $0.10 million, or 0.5%, for the quarter.